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Exchange 2010 451 4.4.0 Primary Target IP address responded 421 4.2.1 unable to conne

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  • Exchange 2010 451 4.4.0 Primary Target IP address responded 421 4.2.1 unable to conne

    have a new exchange 2010 installed into a forest with a 2007 server already running, the two exchange servers serve different domains, on the 2010 server all out going messages sit in queue with the error 451 4.4.0 Primary Target IP address responded 421 4.2.1 unable to connect., i have my send connector set to send to internet. I can ping mail.domain.com for a domain in queue and it replies, i can nslookup and it resolves fine, but i cannot telnet into it at all..any ideas?

  • #2
    Re: Exchange 2010 451 4.4.0 Primary Target IP address responded 421 4.2.1 unable to c

    if you cannot telnet to iot, something is blocking it somewhere.

    Either the remote server isn't actually accepting mail on port 25, or your firewall needs to be reviewed

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